Biosynthesis of mycobacterial arabinogalactan: identification of a novel α(1→3) arabinofuranosyltransferase

The cell wall mycolyl-arabinogalactan–peptidoglycan complex is essential in mycobacterial species, such as Mycobacterium tuberculosis and is the target of several antitubercular drugs. For instance, ethambutol targets arabinogalactan biosynthesis through inhibition of the arabinofuranosyltransferase...

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Detalhes bibliográficos
Main Authors: Birch, Helen L, Alderwick, Luke J, Bhatt, Apoorva, Rittmann, Doris, Krumbach, Karin, Singh, Albel, Bai, Yu, Lowary, Todd L, Eggeling, Lothar, Besra, Gurdyal S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610374/
https://ncbi.nlm.nih.gov/pubmed/18627460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06354.x
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