Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease

OBJECTIVE: Recent studies have suggested a critical role for toll-like receptor 4 (TLR4) in the development of alcoholic liver disease. As TLR4 is widely expressed throughout the body, it is unclear which TLR4-expressing cell types contribute to alcohol-induced liver damage. METHODS: We selectively...

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Udgivet i:Mol Metab
Main Authors: Jia, Lin, Chang, Xiuli, Qian, Shuwen, Liu, Chen, Lord, Caleb C., Ahmed, Newaz, Lee, Charlotte E., Lee, Syann, Gautron, Laurent, Mitchell, Mack C., Horton, Jay D., Scherer, Philipp E., Elmquist, Joel K.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034037/
https://ncbi.nlm.nih.gov/pubmed/29884546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.05.015
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