Hepatocyte Toll-like Receptor 4 Regulates Obesity-Induced Inflammation and Insulin Resistance

Chronic low-grade inflammation is a hallmark of obesity and thought to contribute to the development of obesity-related insulin resistance. Toll-like receptor 4 (Tlr4) is a key mediator of pro-inflammatory responses. Mice lacking Tlr4s are protected from diet-induced insulin resistance and inflammat...

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Detalhes bibliográficos
Main Authors: Jia, Lin, Vianna, Claudia, Fukuda, Makoto, Berglund, Eric, Liu, Chen, Tao, Caroline, Sun, Kai, Liu, Tiemin, Harper, Matthew, Lee, Charlotte E., Lee, Syann, Scherer, Philipp E., Elmquist, Joel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080408/
https://ncbi.nlm.nih.gov/pubmed/24815961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4878
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