Neuropeptide G Protein-Coupled Receptors as Oncotargets

Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby they are secreted from tumor cells, bind to cell s...

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Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Moody, Terry W., Ramos-Alvarez, Irene, Jensen, Robert T.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033971/
https://ncbi.nlm.nih.gov/pubmed/30008698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00345
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