Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2

Hypoxia is a common feature of solid tumours that promotes invasion and metastatic dissemination. Invadopodia are actin-rich membrane protrusions that direct extracellular matrix proteolysis and facilitate tumour cell invasion. Here, we show that CSRP2, an invadopodial actin bundling protein, is upr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Hoffmann, Céline, Mao, Xianqing, Brown-Clay, Joshua, Moreau, Flora, Al Absi, Antoun, Wurzer, Hannah, Sousa, Barbara, Schmitt, Fernando, Berchem, Guy, Janji, Bassam, Thomas, Clément
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033879/
https://ncbi.nlm.nih.gov/pubmed/29976963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28637-x
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares