Silencing NIK potentiates anti-VEGF therapy in a novel 3D model of colorectal cancer angiogenesis

Angiogenesis is essential for colorectal cancer (CRC) progression, as demonstrated by the beneficial clinical effects of therapeutics inhibiting VEGF signaling. However, alternative mechanisms of neovascularization can develop, resulting in treatment failure. Previously we demonstrated NF-κB-inducin...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Maracle, Chrissta X., Jeucken, Kim C.M., Helder, Boy, van Gulik, Thomas M., Steins, Anne, van Laarhoven, Hanneke W.M., Tas, Sander W.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2018
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033358/
https://ncbi.nlm.nih.gov/pubmed/29983872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25442
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