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Enantiodivergent Synthesis of Allenes by Point‐to‐Axial Chirality Transfer

An enantiodivergent method for the synthesis of multiply substituted allenes is described. Highly enantioenriched, point‐chiral boronic esters were synthesized by homologation of α‐seleno alkenyl boronic esters with lithiated carbamates and eliminated to form axially chiral allene products. By emplo...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Armstrong, Roly J., Nandakumar, Meganathan, Dias, Rafael M. P., Noble, Adam, Myers, Eddie L., Aggarwal, Varinder K.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033179/
https://ncbi.nlm.nih.gov/pubmed/29719111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201804446
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