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The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction

A challenge in developing personalized cancer immunotherapies is the prediction of putative cancer‐specific antigens. Currently, predictive algorithms are used to infer binding of peptides to human leukocyte antigen (HLA) heterodimers to aid in the selection of putative epitope targets. One drawback...

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Detalles Bibliográficos
Publicado en:Proteomics
Main Authors: Creech, Amanda L., Ting, Ying S., Goulding, Scott P., Sauld, John F.K., Barthelme, Dominik, Rooney, Michael S., Addona, Terri A., Abelin, Jennifer G.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033110/
https://ncbi.nlm.nih.gov/pubmed/29314742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201700259
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