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The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction

A challenge in developing personalized cancer immunotherapies is the prediction of putative cancer‐specific antigens. Currently, predictive algorithms are used to infer binding of peptides to human leukocyte antigen (HLA) heterodimers to aid in the selection of putative epitope targets. One drawback...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Creech, Amanda L., Ting, Ying S., Goulding, Scott P., Sauld, John F.K., Barthelme, Dominik, Rooney, Michael S., Addona, Terri A., Abelin, Jennifer G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033110/
https://ncbi.nlm.nih.gov/pubmed/29314742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201700259
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