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Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer

INTRODUCTION: Vasculogenic mimicry (VM) describes the formation of an epithelial-independent tumor microcirculation system that differs from traditional angiogenesis. Angiogenesis and the formation of VM are closely related through the cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) pat...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Wang, Sen, Zhang, Zhiyuan, Qian, Wenwei, Ji, Dongjian, Wang, Qingyuan, Ji, Bing, Zhang, Yue, Zhang, Chuan, Sun, Ye, Zhu, Chunyan, Sun, Yueming
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033084/
https://ncbi.nlm.nih.gov/pubmed/29997437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S164982
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