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T cell senescence and CAR-T cell exhaustion in hematological malignancies

T cell senescence has been recognized to play an immunosuppressive role in the aging population and cancer patients. Strategies dedicated to preventing or reversing replicative and premature T cell senescence are required to increase the lifespan of human beings and to reduce the morbidity from canc...

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Detalles Bibliográficos
Publicado en:J Hematol Oncol
Autores principales: Kasakovski, Dimitri, Xu, Ling, Li, Yangqiu
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032767/
https://ncbi.nlm.nih.gov/pubmed/29973238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0629-x
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