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P2RX7 Purinoceptor as a Therapeutic Target—The Second Coming?

The P2RX7 receptor is a unique member of a family of extracellular ATP (eATP)-gated ion channels expressed in immune cells, where its activation triggers the inflammatory cascade. Therefore, P2RX7 has been long investigated as a target in the treatment of infectious and inflammatory diseases. Subseq...

詳細記述

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書誌詳細
出版年:Front Chem
主要な著者: Young, Chris N. J., Górecki, Dariusz C.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032550/
https://ncbi.nlm.nih.gov/pubmed/30003075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00248
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