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Endocrine Disruption at the Androgen Receptor: Employing Molecular Dynamics and Docking for Improved Virtual Screening and Toxicity Prediction

The androgen receptor (AR) is a key target for the development of drugs targeting hormone-dependent prostate cancer, but has also an important role in endocrine disruption. Reliable prediction of the binding of ligands towards the AR is therefore of great relevance. Molecular docking is a powerful c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wahl, Joel, Smieško, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032383/
https://ncbi.nlm.nih.gov/pubmed/29914135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061784
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