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The receptor for advanced glycation endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and exploiting common ground for novel amyloidosis therapies

Proteotoxicity plays a key role in many devastating human disorders, including Alzheimer's, Huntington's and Parkinson's diseases; type 2 diabetes; systemic amyloidosis; and cardiac dysfunction, to name a few. The cellular mechanisms of proteotoxicity in these disorders have been the...

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Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Abedini, Andisheh, Derk, Julia, Schmidt, Ann Marie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032365/
https://ncbi.nlm.nih.gov/pubmed/29664151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3425
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