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Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway

Hepatic stellate cell (HSC) activation is responsible for hepatic fibrogenesis and is associated with an overexpression of transcription 3 (STAT3). Luteolin, a common dietary flavonoid with potent anti-inflammatory properties, has previously demonstrated antifibrogenic properties in HSCs but the mec...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cummins, Claire B., Wang, Xiaofu, Nunez Lopez, Omar, Graham, Gabriel, Tie, Hong-Yan, Zhou, Jia, Radhakrishnan, Ravi S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032316/
https://ncbi.nlm.nih.gov/pubmed/29795016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061567
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