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STAT3 Inhibition Suppresses Hepatic Stellate Cell Fibrogenesis: HJC0123, a Potential Therapeutic Agent for Liver Fibrosis

Hepatic Stellate Cells (HSCs) are the major source of the excessive extracellular matrix (ECM) production that replaces liver parenchyma with fibrous tissue during liver fibrosis. The signal transducer and activator of transcription 3 (STAT3) promotes HCSs survival, proliferation, and activation con...

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Bibliografische gegevens
Gepubliceerd in:RSC Adv
Hoofdauteurs: Lopez, Omar Nunez, Bohanon, Fredrick J., Wang, Xiaofu, Ye, Na, Corsello, Tiziana, Rojas-Khalil, Yesenia, Chen, Haijun, Chen, Haiying, Zhou, Jia, Radhakrishnan, Ravi S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440088/
https://ncbi.nlm.nih.gov/pubmed/28546859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6RA17459K
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