STAT3 Inhibition Suppresses Hepatic Stellate Cell Fibrogenesis: HJC0123, a Potential Therapeutic Agent for Liver Fibrosis

Hepatic Stellate Cells (HSCs) are the major source of the excessive extracellular matrix (ECM) production that replaces liver parenchyma with fibrous tissue during liver fibrosis. The signal transducer and activator of transcription 3 (STAT3) promotes HCSs survival, proliferation, and activation con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RSC Adv
Prif Awduron: Lopez, Omar Nunez, Bohanon, Fredrick J., Wang, Xiaofu, Ye, Na, Corsello, Tiziana, Rojas-Khalil, Yesenia, Chen, Haijun, Chen, Haiying, Zhou, Jia, Radhakrishnan, Ravi S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440088/
https://ncbi.nlm.nih.gov/pubmed/28546859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6RA17459K
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