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Structural Basis for Mutations of Human Aquaporins Associated to Genetic Diseases

Aquaporins (AQPs) are among the best structural-characterized membrane proteins, fulfilling the role of allowing water flux across cellular membranes. Thus far, 34 single amino acid polymorphisms have been reported in HUMSAVAR for human aquaporins as disease-related. They affect AQP2, AQP5 and AQP8,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Calvanese, Luisa, D’Auria, Gabriella, Vangone, Anna, Falcigno, Lucia, Oliva, Romina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032259/
https://ncbi.nlm.nih.gov/pubmed/29799470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061577
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