Meta-Analysis of Autoimmune Regulator-Regulated Genes in Human and Murine Models: A Novel Human Model Provides Insights on the Role of Autoimmune Regulator in Regulating STAT1 and STAT1-Regulated Genes

Autoimmune regulator (AIRE) regulates promiscuous expression of tissue-restricted antigens in medullary epithelial cells (mTEC) of the thymus. To understand the diverse effects of AIRE, it is crucial to elucidate the molecular mechanisms underlying the process of AIRE-regulated gene expression. In t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lovewell, Thomas R. J., McDonagh, Andrew J. G., Messenger, Andrew G., Azzouz, Mimoun, Tazi-Ahnini, Rachid
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031710/
https://ncbi.nlm.nih.gov/pubmed/30002654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01380
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