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Identifying Recrudescent Plasmodium falciparum in Treated Malaria Patients by Real-time PCR and High Resolution Melt Analysis of Genetic Diversity

Recurrent parasitaemia during follow up of clinical trials of antimalarial drug efficacy results from either recrudescence of parasites surviving treatment or from parasites newly emerging from the hepatic stage of infection. Nested PCR is used to distinguish these two possibilities and the techniqu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Beshir, Khalid B., Diallo, Nouhoum, Sutherland, Colin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031682/
https://ncbi.nlm.nih.gov/pubmed/29973679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28179-2
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