Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil

BACKGROUND: Fixed-dose combination antimalarial drugs have played an increasingly important role in the treatment and chemoprophylaxis of falciparum malaria since the worldwide failure of monotherapy with chloroquine. Atovaquone-proguanil is one such combination drug used both for prophylaxis in tra...

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Detalhes bibliográficos
Main Authors: Sutherland, Colin J, Laundy, Matt, Price, Nicholas, Burke, Martina, Fivelman, Quinton L, Pasvol, Geoffrey, Klein, John L, Chiodini, Peter L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640403/
https://ncbi.nlm.nih.gov/pubmed/19021900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-240
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