Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion

Nerve injury-induced hyperactivity of primary sensory neurons in the dorsal root ganglion (DRG) contributes to chronic pain development, but the underlying epigenetic mechanisms remain poorly understood. Here we determined genome-wide changes in DNA methylation in the nervous system in neuropathic p...

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Publicat a:J Neurosci
Autors principals: Garriga, Judit, Laumet, Geoffroy, Chen, Shao-Rui, Zhang, Yuhao, Madzo, Jozef, Issa, Jean-Pierre J., Pan, Hui-Lin, Jelinek, Jaroslav
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031579/
https://ncbi.nlm.nih.gov/pubmed/29875269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2616-17.2018
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