Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG). Here we demonstrate a critical contribution of DRG macrophages, but not those at the nerve injury...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Yu, Xiaobing, Liu, Hongju, Hamel, Katherine A., Morvan, Maelig G., Yu, Stephen, Leff, Jacqueline, Guan, Zhonghui, Braz, Joao M., Basbaum, Allan I.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959328/
https://ncbi.nlm.nih.gov/pubmed/31937758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13839-2
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