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Etiology and treatment of adrenoleukodystrophy: new insights from Drosophila

Adrenoleukodystrophy (ALD) is a fatal progressive neurodegenerative disorder affecting brain white matter. The most common form of ALD is X-linked (X-ALD) and results from mutation of the ABCD1-encoded very-long-chain fatty acid (VLCFA) transporter. X-ALD is clinically heterogeneous, with the cerebr...

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Bibliografiske detaljer
Udgivet i:Dis Model Mech
Main Authors: Gordon, Hannah B., Valdez, Lourdes, Letsou, Anthea
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031365/
https://ncbi.nlm.nih.gov/pubmed/29739804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031286
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