A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disorder caused by mutations in the dystrophin gene, with an incidence of 1 in 3500 in new male births. Mdx mice are widely used as an animal model for DMD. However, these mice do not faithfully recapitulate DMD patients in many aspects...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Sui, Tingting, Lau, Yeh Siang, Liu, Di, Liu, Tingjun, Xu, Li, Gao, Yandi, Lai, Liangxue, Li, Zhanjun, Han, Renzhi
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031364/
https://ncbi.nlm.nih.gov/pubmed/29871865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032201
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