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Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations

Limb girdle muscular dystrophy type 2L (LGMD2L) and Miyoshi myopathy type 3 (MMD3) are autosomal recessive muscular dystrophy caused by mutations in the gene encoding anoctamin-5 (ANO5), which belongs to the anoctamin protein family. Two independent lines of mice with complete disruption of ANO5 tra...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Sui, Tingting, Xu, Li, Lau, Yeh Siang, Liu, Di, Liu, Tingjun, Gao, Yandi, Lai, Liangxue, Han, Renzhi, Li, Zhanjun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964072/
https://ncbi.nlm.nih.gov/pubmed/29789544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0674-y
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