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Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations

Limb girdle muscular dystrophy type 2L (LGMD2L) and Miyoshi myopathy type 3 (MMD3) are autosomal recessive muscular dystrophy caused by mutations in the gene encoding anoctamin-5 (ANO5), which belongs to the anoctamin protein family. Two independent lines of mice with complete disruption of ANO5 tra...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Sui, Tingting, Xu, Li, Lau, Yeh Siang, Liu, Di, Liu, Tingjun, Gao, Yandi, Lai, Liangxue, Han, Renzhi, Li, Zhanjun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964072/
https://ncbi.nlm.nih.gov/pubmed/29789544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0674-y
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