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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin

Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the drug and the cytotoxic effect in patients. Here,...

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Publicat a:Dis Model Mech
Autors principals: García-Rodríguez, Francisco Javier, Martínez-Fernández, Carmen, Brena, David, Kukhtar, Dmytro, Serrat, Xènia, Nadal, Ernest, Boxem, Mike, Honnen, Sebastian, Miranda-Vizuete, Antonio, Villanueva, Alberto, Cerón, Julián
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031354/
https://ncbi.nlm.nih.gov/pubmed/29752286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.033506
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