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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin

Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the drug and the cytotoxic effect in patients. Here,...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: García-Rodríguez, Francisco Javier, Martínez-Fernández, Carmen, Brena, David, Kukhtar, Dmytro, Serrat, Xènia, Nadal, Ernest, Boxem, Mike, Honnen, Sebastian, Miranda-Vizuete, Antonio, Villanueva, Alberto, Cerón, Julián
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031354/
https://ncbi.nlm.nih.gov/pubmed/29752286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.033506
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