In Vitro and In Vivo Delivery of siRNA via VIPER Polymer System to Lung Cells

The block copolymer VIPER (virus-inspired polymer for endosomal release) has been reported to be a promising novel delivery system of DNA plasmids both in vitro and in vivo. VIPER is comprised of a polycation segment for condensation of nucleic acids as well as a pH-sensitive segment that exposes th...

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Pubblicato in:J Control Release
Autori principali: Feldmann, Daniel P, Cheng, Yilong, Kandil, Rima, Xie, Yuran, Mohammadi, Mariam, Harz, Hartmann, Sharma, Akhil, Peeler, David J, Moszczynska, Anna, Leonhardt, Heinrich, Pun, Suzie H., Merkel, Olivia M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031299/
https://ncbi.nlm.nih.gov/pubmed/29474962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.02.017
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