Differential preventive activity of sulindac and atorvastatin in Apc(+/Min-FCCC)mice with or without colorectal adenomas

OBJECTIVE: The response of subjects to preventive intervention is heterogeneous. The goal of this study was to determine if the efficacy of a chemopreventive agent differs in non-tumour-bearing animals versus those with colorectal tumours. Sulindac and/or atorvastatin was administered to Apc(+/Min-F...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Chang, Wen-Chi L, Jackson, Christina, Riel, Stacy, Cooper, Harry S, Devarajan, Karthik, Hensley, Harvey H, Zhou, Yan, Vanderveer, Lisa A, Nguyen, Minhhuyen T, Clapper, Margie L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Colon
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031273/
https://ncbi.nlm.nih.gov/pubmed/29122850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-313942
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