The somatic mutation landscape of premalignant colorectal adenoma

OBJECTIVE: There are few studies which characterised the molecular alterations in premalignant colorectal adenomas. Our major goal was to establish colorectal adenoma genome atlas and identify molecular markers of progression from colorectal adenoma to adenocarcinoma. DESIGN: Whole-exome sequencing...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Lin, Shu-Hong, Raju, Gottumukkala S, Huff, Chad, Ye, Yuanqing, Gu, Jian, Chen, Jiun-Sheng, Hildebrandt, Michelle A T, Liang, Han, Menter, David G, Morris, Jeffery, Hawk, Ernest, Stroehlein, John R, Futreal, Andrew, Kopetz, Scott, Mishra, Lopa, Wu, Xifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Gut 2018
Assuntos:
Colon
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031265/
https://ncbi.nlm.nih.gov/pubmed/28607096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313573
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