Cardiac myosin-binding protein C is a novel marker of myocardial injury and fibrosis in aortic stenosis

OBJECTIVE: Cardiac myosin-binding protein C (cMyC) is an abundant sarcomeric protein and novel highly specific marker of myocardial injury. Myocyte death characterises the transition from hypertrophy to replacement myocardial fibrosis in advanced aortic stenosis. We hypothesised that serum cMyC conc...

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Bibliographische Detailangaben
Veröffentlicht in:Heart
Hauptverfasser: Anand, Atul, Chin, Calvin, Shah, Anoop S V, Kwiecinski, Jacek, Vesey, Alex, Cowell, Joanna, Weber, Ekkehard, Kaier, Thomas, Newby, David E, Dweck, Marc, Marber, Michael S, Mills, Nicholas L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2018
Schlagworte:
Valvular Heart Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031261/
https://ncbi.nlm.nih.gov/pubmed/29196542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/heartjnl-2017-312257
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