Cardiac myosin-binding protein C is a novel marker of myocardial injury and fibrosis in aortic stenosis

OBJECTIVE: Cardiac myosin-binding protein C (cMyC) is an abundant sarcomeric protein and novel highly specific marker of myocardial injury. Myocyte death characterises the transition from hypertrophy to replacement myocardial fibrosis in advanced aortic stenosis. We hypothesised that serum cMyC conc...

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Bibliographic Details
Published in:Heart
Main Authors: Anand, Atul, Chin, Calvin, Shah, Anoop S V, Kwiecinski, Jacek, Vesey, Alex, Cowell, Joanna, Weber, Ekkehard, Kaier, Thomas, Newby, David E, Dweck, Marc, Marber, Michael S, Mills, Nicholas L
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2018
Subjects:
Valvular Heart Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031261/
https://ncbi.nlm.nih.gov/pubmed/29196542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/heartjnl-2017-312257
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