Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses

INTRODUCTION: Current models posit a sequence of amyloid β (Aβ), tau, atrophy, and cognitive change leading to Alzheimer's disease, but ambiguities remain. We examined these sequences via serial mediations. METHODS: We studied normal controls, early mild cognitive impairment, and late mild cogn...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Fletcher, Evan, Filshtein, Teresa Jenica, Harvey, Danielle, Renaud, Alice, Mungas, Dan, DeCarli, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Neuroimaging
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031152/
https://ncbi.nlm.nih.gov/pubmed/29984299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2018.04.001
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