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Passenger mutations can accelerate tumour suppressor gene inactivation in cancer evolution
Carcinogenesis is an evolutionary process whereby cells accumulate multiple mutations. Besides the ‘driver mutations’ that cause the disease, cells also accumulate a number of other mutations with seemingly no direct role in this evolutionary process. They are called passenger mutations. While it ha...
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| Udgivet i: | J R Soc Interface |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030626/ https://ncbi.nlm.nih.gov/pubmed/29875280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2017.0967 |
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