Folate Receptor Alpha Peptide Vaccine Generates Immunity in Breast and Ovarian Cancer Patients

PURPOSE: Folate receptor alpha (FR) is overexpressed in several cancers. Endogenous immunity to the FR has been demonstrated in patients and suggests the feasibility of targeting FR with vaccine or other immune therapies. CD4 helper T cells are central to the development of coordinated immunity and...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Kalli, Kimberly R., Block, Matthew S., Kasi, Pashtoon M., Erskine, Courtney L., Hobday, Timothy J., Dietz, Allan B., Padley, Douglas J., Gustafson, Michael P., Visscher, Dan W., Puglisi-Knutson, Danell J., Shreeder, Barath, Mangskau, Toni K., Wilson, Glynn, Knutson, Keith L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030477/
https://ncbi.nlm.nih.gov/pubmed/29545464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2499
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