Folate Receptor Alpha Peptide Vaccine Generates Immunity in Breast and Ovarian Cancer Patients

PURPOSE: Folate receptor alpha (FR) is overexpressed in several cancers. Endogenous immunity to the FR has been demonstrated in patients and suggests the feasibility of targeting FR with vaccine or other immune therapies. CD4 helper T cells are central to the development of coordinated immunity and...

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Publicado en:Clin Cancer Res
Main Authors: Kalli, Kimberly R., Block, Matthew S., Kasi, Pashtoon M., Erskine, Courtney L., Hobday, Timothy J., Dietz, Allan B., Padley, Douglas J., Gustafson, Michael P., Visscher, Dan W., Puglisi-Knutson, Danell J., Shreeder, Barath, Mangskau, Toni K., Wilson, Glynn, Knutson, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030477/
https://ncbi.nlm.nih.gov/pubmed/29545464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2499
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