Folate Receptor Alpha Peptide Vaccine Generates Immunity in Breast and Ovarian Cancer Patients

PURPOSE: Folate receptor alpha (FR) is overexpressed in several cancers. Endogenous immunity to the FR has been demonstrated in patients and suggests the feasibility of targeting FR with vaccine or other immune therapies. CD4 helper T cells are central to the development of coordinated immunity and...

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Publicat a:Clin Cancer Res
Autors principals: Kalli, Kimberly R., Block, Matthew S., Kasi, Pashtoon M., Erskine, Courtney L., Hobday, Timothy J., Dietz, Allan B., Padley, Douglas J., Gustafson, Michael P., Visscher, Dan W., Puglisi-Knutson, Danell J., Shreeder, Barath, Mangskau, Toni K., Wilson, Glynn, Knutson, Keith L.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030477/
https://ncbi.nlm.nih.gov/pubmed/29545464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2499
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