Interaction Between Macrophage Migration Inhibitory Factor and CD74 in Human Immunodeficiency Virus Type I Infected Primary Monocyte-Derived Macrophages Triggers the Production of Proinflammatory Mediators and Enhances Infection of Unactivated CD4(+) T Cells

Understanding the mechanisms of human immunodeficiency virus type I (HIV-1) pathogenesis would facilitate the identification of new therapeutic targets to control the infection in face of current antiretroviral therapy limitations. CD74 membrane expression is upregulated in HIV-1-infected cells and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Trifone, César, Salido, Jimena, Ruiz, María Julia, Leng, Lin, Quiroga, María Florencia, Salomón, Horacio, Bucala, Richard, Ghiglione, Yanina, Turk, Gabriela
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030361/
https://ncbi.nlm.nih.gov/pubmed/29997630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01494
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