TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells

CD74 is a multifunctional protein and a receptor for Macrophage Migration Inhibitory Factor (MIF) and MIF-2 / D-dopachrome tautomerase (DDT) cytokines, upregulated in diabetic kidney disease. However, the drivers of CD74 expression and DDT function in kidney cells are poorly characterized. TWEAK is...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Valiño-Rivas, Lara, Cuarental, Leticia, Grana, Osvaldo, Bucala, Richard, Leng, Lin, Sanz, Ana, Gomez, Gonzalo, Ortiz, Alberto, Sanchez-Niño, Maria Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010292/
https://ncbi.nlm.nih.gov/pubmed/29924850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199391
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