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The regio-selective synthesis of 10-hydroxy camptothecin norcantharidin conjugates and their biological activity evaluation in vitro

A series of conjugates of 10-hydroxy camptothecin (HCPT) with functionalized norcantharidin derivatives were regio-selectively synthesized in the condition of (3-dimethylaminopropyl) ethyl-carbodiimide monohydrochloride in a moderate yield. The synthesized conjugate HCPT pro-drugs can also suppress...

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Xehetasun bibliografikoak
Argitaratua izan da:R Soc Open Sci
Egile Nagusiak: Zhao, Chang K., Li, Chan, Wang, Xian H., Bao, Yu J., Yang, Fu H., Huang, Mei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society Publishing 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030274/
https://ncbi.nlm.nih.gov/pubmed/30110459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.172317
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