Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

The incidence of Plasmodium vivax infection has declined markedly in Malaysia over the past decade despite evidence of high-grade chloroquine resistance. Here we investigate the genetic changes in a P. vivax population approaching elimination in 51 isolates from Sabah, Malaysia and compare these wit...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Auburn, Sarah, Benavente, Ernest D., Miotto, Olivo, Pearson, Richard D., Amato, Roberto, Grigg, Matthew J., Barber, Bridget E., William, Timothy, Handayuni, Irene, Marfurt, Jutta, Trimarsanto, Hidayat, Noviyanti, Rintis, Sriprawat, Kanlaya, Nosten, Francois, Campino, Susana, Clark, Taane G., Anstey, Nicholas M., Kwiatkowski, Dominic P., Price, Ric N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030216/
https://ncbi.nlm.nih.gov/pubmed/29968722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04965-4
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