Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

The incidence of Plasmodium vivax infection has declined markedly in Malaysia over the past decade despite evidence of high-grade chloroquine resistance. Here we investigate the genetic changes in a P. vivax population approaching elimination in 51 isolates from Sabah, Malaysia and compare these wit...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Auburn, Sarah, Benavente, Ernest D., Miotto, Olivo, Pearson, Richard D., Amato, Roberto, Grigg, Matthew J., Barber, Bridget E., William, Timothy, Handayuni, Irene, Marfurt, Jutta, Trimarsanto, Hidayat, Noviyanti, Rintis, Sriprawat, Kanlaya, Nosten, Francois, Campino, Susana, Clark, Taane G., Anstey, Nicholas M., Kwiatkowski, Dominic P., Price, Ric N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030216/
https://ncbi.nlm.nih.gov/pubmed/29968722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04965-4
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky