The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer

Therapy resistance represents a clinical challenge for advanced non-small cell lung cancer (NSCLC), which still remains an incurable disease. There is growing evidence that cancer-initiating or cancer stem cells (CSCs) provide a reservoir of slow-growing dormant populations of cells with tumor-initi...

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Udgivet i:Cell Death Differ
Main Authors: Fernandez, Harvey R., Gadre, Shreyas M., Tan, Mingjun, Graham, Garrett T., Mosaoa, Rami, Ongkeko, Martin S., Kim, Kyu Ah, Riggins, Rebecca B., Parasido, Erika, Petrini, Iacopo, Pacini, Simone, Cheema, Amrita, Varghese, Rency, Ressom, Habtom W, Zhang, Yuwen, Albanese, Christopher, Üren, Aykut, Paige, Mikell, Giaccone, Giuseppe, Avantaggiati, Maria Laura
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030199/
https://ncbi.nlm.nih.gov/pubmed/29651165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0101-z
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