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The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer

Therapy resistance represents a clinical challenge for advanced non-small cell lung cancer (NSCLC), which still remains an incurable disease. There is growing evidence that cancer-initiating or cancer stem cells (CSCs) provide a reservoir of slow-growing dormant populations of cells with tumor-initi...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Fernandez, Harvey R., Gadre, Shreyas M., Tan, Mingjun, Graham, Garrett T., Mosaoa, Rami, Ongkeko, Martin S., Kim, Kyu Ah, Riggins, Rebecca B., Parasido, Erika, Petrini, Iacopo, Pacini, Simone, Cheema, Amrita, Varghese, Rency, Ressom, Habtom W, Zhang, Yuwen, Albanese, Christopher, Üren, Aykut, Paige, Mikell, Giaccone, Giuseppe, Avantaggiati, Maria Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030199/
https://ncbi.nlm.nih.gov/pubmed/29651165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0101-z
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