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Modulation of M1/M2 polarization by capsaicin contributes to the survival of dopaminergic neurons in the lipopolysaccharide-lesioned substantia nigra in vivo

The present study examined the neuroprotective effects of capsaicin (CAP) and explored their underlying mechanisms in a lipopolysaccharide (LPS)-lesioned inflammatory rat model of Parkinson’s dieases (PD). LPS was unilaterally injected into the substantia nigra (SN) in the absence or presence of CAP...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Bok, Eugene, Chung, Young Cheul, Kim, Ki-Suk, Baik, Hyung Hwan, Shin, Won-Ho, Jin, Byung Kwan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030094/
https://ncbi.nlm.nih.gov/pubmed/29968707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0111-4
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