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RNA Nanoparticle Distribution and Clearance in the Eye after Subconjunctival Injection with and without Thermosensitive Hydrogels

Thermodynamically and chemically stable RNA nanoparticles derived from the three-way junction (3WJ) of the pRNA from bacteriophage phi29 DNA packaging motor were examined previously for ocular delivery. It was reported that RNA nanoparticles with tri-way shape entered the corneal cells but not the r...

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Dades bibliogràfiques
Publicat a:J Control Release
Autors principals: Shi, Zhanquan, Li, S. Kevin, Charoenputtakun, Ponwanit, Liu, Chia-Yang, Jasinski, Daniel, Guo, Peixuan
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029979/
https://ncbi.nlm.nih.gov/pubmed/29170141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.11.028
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