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PLGA Spherical Nucleic Acids

A new class of polymer spherical nucleic acid (SNA) conjugates comprised of poly(lactic-co-glycolic acid) (PLGA) nanoparticle (NP) cores is reported. The nucleic acid shell that defines the PLGA-SNA exhibits a half-life of more than 2 h in fetal bovine serum. Importantly, the PLGA-SNAs can be utiliz...

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Publicado en:Adv Mater
Main Authors: Zhu, Shengshuang, Xing, Hang, Gordiichuk, Pavlo, Park, Jungsoo, Mirkin, Chad A.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029717/
https://ncbi.nlm.nih.gov/pubmed/29682820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201707113
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