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Endothelin type A receptors mediate pain in a mouse model of sickle cell disease

Sickle cell disease is associated with acute painful episodes and chronic intractable pain. Endothelin-1, a known pain inducer, is elevated in the blood plasma of both sickle cell patients and mouse models of sickle cell disease. We show here that the levels of endothelin-1 and its endothelin type A...

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Bibliographische Detailangaben
Veröffentlicht in:Haematologica
Hauptverfasser: Lutz, Brianna Marie, Wu, Shaogen, Gu, Xiyao, Atianjoh, Fidelis E., Li, Zhen, Fox, Brandon M., Pollock, David M., Tao, Yuan-Xiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029538/
https://ncbi.nlm.nih.gov/pubmed/29545351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.187013
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