Inhibition of the hepatic Nlrp3 protects dopaminergic neurons via attenuating systemic inflammation in a MPTP/p mouse model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder with progressive loss of dopaminergic (DA) neurons. Systemic inflammation is shown to initiate and exacerbate DA neuronal degeneration in the substantia nigra. The infiltration and transformation of immune cells from the peripheral...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Neuroinflammation
Autores principales: Qiao, Chen, Zhang, Qian, Jiang, Qingling, Zhang, Ting, Chen, Miaomiao, Fan, Yi, Ding, Jianhua, Lu, Ming, Hu, Gang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029067/
https://ncbi.nlm.nih.gov/pubmed/29966531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1236-z
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares