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Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain

Small noncoding RNAs (sncRNAs) regulate many genes in eukaryotic cells. Hua enhancer 1 (Hen1) is a 2′-O-methyltransferase that adds a methyl group to the 2′-OH of the 3′-terminal nucleotide of sncRNAs. The types and properties of sncRNAs may vary among different species, and the domain composition,...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Peng, Ling, Zhang, Fengjuan, Shang, Renfu, Wang, Xueyan, Chen, Jiayi, Chou, James J., Ma, Jinbiao, Wu, Ligang, Huang, Ying
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028966/
https://ncbi.nlm.nih.gov/pubmed/29703750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000837
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