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Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain
Small noncoding RNAs (sncRNAs) regulate many genes in eukaryotic cells. Hua enhancer 1 (Hen1) is a 2′-O-methyltransferase that adds a methyl group to the 2′-OH of the 3′-terminal nucleotide of sncRNAs. The types and properties of sncRNAs may vary among different species, and the domain composition,...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028966/ https://ncbi.nlm.nih.gov/pubmed/29703750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000837 |
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