Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2–dependent maturation of dendritic cells

Targeting of Mycobacterium tuberculosis (MTB) PE/PPE antigens that induce type 1 helper T cell (Th1) and Th17 responses represents a crucial strategy for the development of tuberculosis (TB) vaccines. However, only a few PE/PPE antigens induce these responses. Here, we sought to determine how the ce...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Su, Haibo, Zhang, Zhen, Liu, Zijian, Peng, Baozhou, Kong, Cong, Wang, Honghai, Zhang, Zhi, Xu, Ying
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028961/
https://ncbi.nlm.nih.gov/pubmed/29739853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001696
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