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The tetrameric structure of sialic acid–synthesizing UDP-GlcNAc 2-epimerase from Acinetobacter baumannii: A comparative study with human GNE

Sialic acid presentation on the cell surface by some pathogenic strains of bacteria allows their escape from the host immune system. It is one of the major virulence factors. Bacterial biosynthesis of sialic acids starts with the conversion of UDP-GlcNAc to UDP and ManNAc by a hydrolyzing 2-epimeras...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Ko, Tzu-Ping, Lai, Shu-Jung, Hsieh, Tung-Ju, Yang, Chia-Shin, Chen, Yeh
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028959/
https://ncbi.nlm.nih.gov/pubmed/29764940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001971
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